H2N2V1, France, Analysis, bibRecord, 000050

Synthesis of novel pentacyclic triterpene–Neu5Ac2en derivatives and investigation of their in vitro anti-influenza entry activity††Dedicated to Professor Lihe Zhang on the Occasion of His 80th Birthday.‡‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c7md00245a

Identifieur interne : 000050 ( France/Analysis ); précédent : 000049; suivant : 000051

Synthesis of novel pentacyclic triterpene–Neu5Ac2en derivatives and investigation of their in vitro anti-influenza entry activity††Dedicated to Professor Lihe Zhang on the Occasion of His 80th Birthday.‡‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c7md00245a

Auteurs : Yongying Shi ; Longlong Si ; Xu Han ; Zibo Fan ; Shouxin Wang [République populaire de Chine] ; Man Li ; Jiaqi Sun ; Yongmin Zhang [France] ; Demin Zhou ; Sulong Xiao

Source :

MedChemComm [ 2040-2503 ] ; 2017.

RBID : PMC:6072002

Abstract

The C-4 hydroxyl group of sialic acid is not important for its binding with hemagglutinin and could be replaced with hydrophobic moieties.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072002

DOI: 10.1039/c7md00245a
PubMed: 30108865
PubMed Central: 6072002

Affiliations:

Links to Exploration step

PMC:6072002

Le document en format XML

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 anti-influenza entry activity<xref ref-type="fn" rid="fn1">†</xref>
<fn id="fn1"><p>†Dedicated to Professor Lihe Zhang on the Occasion of His 80th Birthday.</p>
</fn>
<xref ref-type="fn" rid="fn2">‡</xref>
<fn id="fn2"><p>‡Electronic supplementary information (ESI) available. See DOI: <uri xlink:type="simple" xlink:href="https://doi.org/10.1039/c7md00245a">10.1039/c7md00245a</uri>
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<author><name sortKey="Shi, Yongying" sort="Shi, Yongying" uniqKey="Shi Y" first="Yongying" last="Shi">Yongying Shi</name>
<affiliation><nlm:aff id="affa"> State Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email:<email>slxiao@bjmu.edu.cn</email>
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<author><name sortKey="Si, Longlong" sort="Si, Longlong" uniqKey="Si L" first="Longlong" last="Si">Longlong Si</name>
<affiliation><nlm:aff id="affa"> State Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email:<email>slxiao@bjmu.edu.cn</email>
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<author><name sortKey="Han, Xu" sort="Han, Xu" uniqKey="Han X" first="Xu" last="Han">Xu Han</name>
<affiliation><nlm:aff id="affa"> State Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email:<email>slxiao@bjmu.edu.cn</email>
</nlm:aff>
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<author><name sortKey="Fan, Zibo" sort="Fan, Zibo" uniqKey="Fan Z" first="Zibo" last="Fan">Zibo Fan</name>
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<author><name sortKey="Wang, Shouxin" sort="Wang, Shouxin" uniqKey="Wang S" first="Shouxin" last="Wang">Shouxin Wang</name>
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<wicri:regionArea> Institut Parisien de Chimie Moléculaire , CNRS UMR 8232 , Sorbonne Universités , UPMC Univ Paris 06 , 4 place Jussieu , 75005 Paris </wicri:regionArea>
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<author><name sortKey="Zhou, Demin" sort="Zhou, Demin" uniqKey="Zhou D" first="Demin" last="Zhou">Demin Zhou</name>
<affiliation><nlm:aff id="affa"> State Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email:<email>slxiao@bjmu.edu.cn</email>
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<author><name sortKey="Xiao, Sulong" sort="Xiao, Sulong" uniqKey="Xiao S" first="Sulong" last="Xiao">Sulong Xiao</name>
<affiliation><nlm:aff id="affa"> State Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email:<email>slxiao@bjmu.edu.cn</email>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Synthesis of novel pentacyclic triterpene–Neu5Ac2en derivatives and investigation of their <italic>in vitro</italic>
 anti-influenza entry activity<xref ref-type="fn" rid="fn1">†</xref>
<fn id="fn1"><p>†Dedicated to Professor Lihe Zhang on the Occasion of His 80th Birthday.</p>
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<fn id="fn2"><p>‡Electronic supplementary information (ESI) available. See DOI: <uri xlink:type="simple" xlink:href="https://doi.org/10.1039/c7md00245a">10.1039/c7md00245a</uri>
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<author><name sortKey="Han, Xu" sort="Han, Xu" uniqKey="Han X" first="Xu" last="Han">Xu Han</name>
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<author><name sortKey="Fan, Zibo" sort="Fan, Zibo" uniqKey="Fan Z" first="Zibo" last="Fan">Zibo Fan</name>
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</nlm:aff>
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<author><name sortKey="Wang, Shouxin" sort="Wang, Shouxin" uniqKey="Wang S" first="Shouxin" last="Wang">Shouxin Wang</name>
<affiliation><nlm:aff id="affa"> State Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email:<email>slxiao@bjmu.edu.cn</email>
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<author><name sortKey="Li, Man" sort="Li, Man" uniqKey="Li M" first="Man" last="Li">Man Li</name>
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<author><name sortKey="Sun, Jiaqi" sort="Sun, Jiaqi" uniqKey="Sun J" first="Jiaqi" last="Sun">Jiaqi Sun</name>
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</nlm:aff>
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<author><name sortKey="Zhang, Yongmin" sort="Zhang, Yongmin" uniqKey="Zhang Y" first="Yongmin" last="Zhang">Yongmin Zhang</name>
<affiliation wicri:level="3"><nlm:aff id="affb"> Institut Parisien de Chimie Moléculaire , CNRS UMR 8232 , Sorbonne Universités , UPMC Univ Paris 06 , 4 place Jussieu , 75005 Paris , France</nlm:aff>
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<author><name sortKey="Zhou, Demin" sort="Zhou, Demin" uniqKey="Zhou D" first="Demin" last="Zhou">Demin Zhou</name>
<affiliation><nlm:aff id="affa"> State Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email:<email>slxiao@bjmu.edu.cn</email>
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<author><name sortKey="Xiao, Sulong" sort="Xiao, Sulong" uniqKey="Xiao S" first="Sulong" last="Xiao">Sulong Xiao</name>
<affiliation><nlm:aff id="affa"> State Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email:<email>slxiao@bjmu.edu.cn</email>
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<front><div type="abstract" xml:lang="en"><p><graphic xlink:href="c7md00245a-ga.jpg" id="ga" position="float" orientation="portrait"></graphic>
The C-4 hydroxyl group of sialic acid is not important for its binding with hemagglutinin and could be replaced with hydrophobic moieties.</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
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<region><li>Île-de-France</li>
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<settlement><li>Paris </li>
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<tree><noCountry><name sortKey="Fan, Zibo" sort="Fan, Zibo" uniqKey="Fan Z" first="Zibo" last="Fan">Zibo Fan</name>
<name sortKey="Han, Xu" sort="Han, Xu" uniqKey="Han X" first="Xu" last="Han">Xu Han</name>
<name sortKey="Li, Man" sort="Li, Man" uniqKey="Li M" first="Man" last="Li">Man Li</name>
<name sortKey="Shi, Yongying" sort="Shi, Yongying" uniqKey="Shi Y" first="Yongying" last="Shi">Yongying Shi</name>
<name sortKey="Si, Longlong" sort="Si, Longlong" uniqKey="Si L" first="Longlong" last="Si">Longlong Si</name>
<name sortKey="Sun, Jiaqi" sort="Sun, Jiaqi" uniqKey="Sun J" first="Jiaqi" last="Sun">Jiaqi Sun</name>
<name sortKey="Xiao, Sulong" sort="Xiao, Sulong" uniqKey="Xiao S" first="Sulong" last="Xiao">Sulong Xiao</name>
<name sortKey="Zhou, Demin" sort="Zhou, Demin" uniqKey="Zhou D" first="Demin" last="Zhou">Demin Zhou</name>
</noCountry>
<country name="République populaire de Chine"><noRegion><name sortKey="Wang, Shouxin" sort="Wang, Shouxin" uniqKey="Wang S" first="Shouxin" last="Wang">Shouxin Wang</name>
</noRegion>
</country>
<country name="France"><region name="Île-de-France"><name sortKey="Zhang, Yongmin" sort="Zhang, Yongmin" uniqKey="Zhang Y" first="Yongmin" last="Zhang">Yongmin Zhang</name>
</region>
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   |texte=   Synthesis of novel pentacyclic triterpene–Neu5Ac2en derivatives and investigation of their in vitro anti-influenza entry activity††Dedicated to Professor Lihe Zhang on the Occasion of His 80th Birthday.‡‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c7md00245a
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Synthesis of novel pentacyclic triterpene–Neu5Ac2en derivatives and investigation of their in vitro anti-influenza entry activity††Dedicated to Professor Lihe Zhang on the Occasion of His 80th Birthday.‡‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c7md00245a

Synthesis of novel pentacyclic triterpene–Neu5Ac2en derivatives and investigation of their in vitro anti-influenza entry activity††Dedicated to Professor Lihe Zhang on the Occasion of His 80th Birthday.‡‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c7md00245a

Source :

Abstract

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